Sequencing for oxidative DNA damage at single-nucleotide resolution with click-code-seq v2.0.

ABSTRACT: Oxidative damage to DNA nucleotides has many cellular outcomes that could be aided by the development of sequencing methods. Herein, the previously reported click-code-seq method for sequencing a single damage type is redeveloped to enable the sequencing of many damage types by making simple changes to the protocol (i.e., click-code-seq v2.0).

SUBMITTER: Xiao S 

PROVIDER: S-EPMC10909242 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature