MRI-guided radiotherapy in twenty fractions for localised prostate cancer; results from the MOMENTUM study.

ABSTRACT:

Background and purpose

MRI-guided radiotherapy (MRIgRT) offers multiple potential advantages over CT-guidance. This study examines the potential clinical benefits of MRIgRT for men with localised prostate cancer, in the setting of moderately hypofractionated radiotherapy. We evaluate two-year toxicity outcomes, early biochemical response and patient-reported outcomes (PRO), using data obtained from a multicentre international registry study, for the first group of patients with prostate cancer who underwent treatment on a 1.5 T MR-Linac.

Materials and methods

Patients who were enrolled within the MOMENTUM study and received radical treatment with 60 Gy in 20 fractions were identified. PSA levels and CTCAE version 5.0 toxicity data were measured at follow-up visits. Those pat

SUBMITTER: Sritharan K 

PROVIDER: S-EPMC10909700 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature