Efficacy and safety of Argatroban in patients with acute ischemic stroke: a systematic review and meta-analysis.

ABSTRACT:

Objective

Argatroban is a highly promising drug for the treatment of acute ischemic stroke (AIS), but there is currently insufficient strong evidence regarding the efficacy and safety of using Argatroban in the treatment of AIS. Therefore, we conducted a systematic review and meta-analysis to evaluate the effectiveness and safety of Argatroban in the treatment of AIS.

Methods

Articles on PubMed, Embase and the Cochrane Library databases were searched from these websites' inceptions to 2th February 2023. Randomized controlled trials and observational studies on Argatroban therapy for acute ischemic stroke were included. Meta-analyses were conducted using a random-effects model.

Results

Fourteen studies involving 10,315 patients were included in the meta-analysis. The r

SUBMITTER: Cheng Y 

PROVIDER: S-EPMC10909846 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature