Epidemiology and Functional Impact of Early Peripheral Neuropathy Signs in Older Adults from a General Population.

ABSTRACT:

Introduction

Peripheral neuropathy (PN) becomes more common with increasing life expectancy, but general population prevalence estimates are lacking. We investigated an epidemiological distribution of signs of PN among 2,996 community-dwelling participants in Good Aging in Skåne Study, age 60-97, and their impact on physical and autonomic function.

Methods

Signs of PN were measured with Utah Early Neuropathy Scale (UENS). Associations between UENS and physical tests, pain, and dysautonomic phenomena were calculated for each sex, adjusted for age, with estimated marginal means (EMM) and odds ratios (ORs) in four UENS quantiles (Q1-Q4).

Results

Participants in Q4 had worse EMM for: time to complete Timed Up and Go test (Q4-Q1: male 10.8-9.6 s; female 11.7-10.2 s), 15 m

SUBMITTER: Bronge W 

PROVIDER: S-EPMC10911163 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature