Identifying sensitive windows of prenatal household air pollution on birth weight and infant pneumonia risk to inform future interventions.

ABSTRACT:

Background

Prenatal household air pollution impairs birth weight and increases pneumonia risk however time-varying associations have not been elucidated and may have implications for the timing of public health interventions.

Methods

The Ghana Randomized Air Pollution and Health Study (GRAPHS) enrolled 1,414 pregnant women from Kintampo, Ghana and measured personal carbon monoxide (CO) exposure four times over pregnancy. Birth weight was measured within 72-hours of birth. Fieldworkers performed weekly pneumonia surveillance and referred sick children to study physicians. The primary pneumonia outcome was one or more physician-diagnosed severe pneumonia episode in the first year of life. We employed reverse distributed lag models to examine time-varying associations between p

SUBMITTER: Kaali S 

PROVIDER: S-EPMC10911234 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature