Two Interventions on Pathologic Nodal Staging in a Population-Based Lung Cancer Resection Cohort.

ABSTRACT:

Background

Despite its prognostic importance, poor pathologic nodal staging of lung cancer prevails. We evaluated the impact of 2 interventions to improve pathologic nodal staging.

Methods

We implemented a lymph node specimen collection kit to improve intraoperative lymph node collection (surgical intervention) and a novel gross dissection method for intrapulmonary node retrieval (pathology intervention) in nonrandomized stepped-wedge fashion, involving 12 hospitals and 7 pathology groups. We used standard statistical methods to compare surgical quality and survival of patients who had neither intervention (group 1), pathology intervention only (group 2), surgical intervention only (group 3), and both interventions (group 4).

Results

Of 4019 patients from 2009 to 2021

SUBMITTER: Osarogiagbon RU 

PROVIDER: S-EPMC10912374 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature