Competing contextual processes rely on the infralimbic and prelimbic medial prefrontal cortices in the rat.

ABSTRACT: Ambiguous relationships between events may be established using interference procedures such as latent inhibition, extinction or counterconditioning. Under these conditions, the retrieval of individual associations between a stimulus and outcome is affected by contextual cues. To examine the roles of the dorsal (prelimbic) and ventral (infralimbic) medial prefrontal cortex in the contextual modulation of such associations, we investigated the context specificity of latent inhibition. Male Lister hooded rats were pre-exposed to two separate stimuli, one in each of two distinct contexts. Both stimuli were then paired with the delivery of mild foot-shock in the same one of these contexts. Finally, the strength of the resultant conditioned emotional response (CER) to each stimulus was assessed

SUBMITTER: George DN 

PROVIDER: S-EPMC10913818 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature