Ontology highlight
ABSTRACT:
SUBMITTER: Yang Y
PROVIDER: S-EPMC10915707 | biostudies-literature | 2024 Apr
REPOSITORIES: biostudies-literature
Yang Ye Y Wu Junyi J Zhu Huiqin H Shi Xiaoqin X Liu Jun J Li Yang Y Wang Min M
Oncology reports 20240223 4
The incidence of thyroid carcinoma (TC) has exhibited a rapid increase in recent years. A proportion of TCs exhibit aggressive behavior. The present study aimed to investigate the potential role of hypoxia‑hypoxia inducible factor 1 subunit α (HIF‑1α)‑periostin axis in the progression of TC. The upregulation of periostin and HIF‑1α expression levels was detected in 95 clinical TC tissues as compared with normal thyroid tissues. Hypoxia promoted the viability and invasion of TC cells and this eff ...[more]