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Early neurological deterioration in patients with acute ischemic stroke is linked to unfavorable cerebral venous outflow.


ABSTRACT:

Introduction

Early neurological deterioration (END) is associated with poor outcomes in patients with acute ischemic stroke due to large vessel occlusion (AIS-LVO). Causes of END after mechanical thrombectomy (MT) include unsuccessful recanalization and reperfusion hemorrhages. However, little is known about END excluding the aforementioned causes. We aimed to investigate factors associated with unexplained END (ENDunexplained) with regard to the cerebral collateral status.

Patients and methods

Multicenter retrospective study of AIS-LVO patients with successful MT (mTICI 2b-3). On admission CT angiography (CTA), pial arterial collaterals and venous outflow (VO) were assessed using the modified Tan-Scale and the Cortical Vein Opacification Score (COVES), respective

SUBMITTER: Heitkamp C 

PROVIDER: S-EPMC10916832 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature