Residues in the murine leukemia virus capsid that differentially govern resistance to mouse Fv1 and human Ref1 restrictions.

ABSTRACT: We identified new residues within a 101-amino-acid stretch of the murine leukemia virus capsid that differentially modulate resistance and susceptibility to the mouse Fv1 and human Ref1 genes. Among these residues, aspartate 92 and histidine 117 are both required for Fv1(b) resistance, whereas the latter is sufficient to confer Ref1 resistance.

SUBMITTER: Lassaux A 

PROVIDER: S-EPMC1091700 | biostudies-literature | 2005 May

REPOSITORIES: biostudies-literature