Complex epistatic interactions between ELF3, PRR9, and PRR7 regulate the circadian clock and plant physiology.
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ABSTRACT: Circadian clocks are endogenous timekeeping mechanisms that coordinate internal physiological responses with the external environment. EARLY FLOWERING3 (ELF3), PSEUDO RESPONSE REGULATOR (PRR9), and PRR7 are essential components of the plant circadian clock and facilitate entrainment of the clock to internal and external stimuli. Previous studies have highlighted a critical role for ELF3 in repressing the expression of PRR9 and PRR7. However, the functional significance of activity in regulating circadian clock dynamics and plant development is unknown. To explore this regulatory dynamic further, we first employed mathematical modeling to simulate the effect of the prr9/prr7 mutation on the elf3 circadian phenotype. These simulations suggested that simultaneous mutations in prr9/prr7 could
SUBMITTER: Yuan L
PROVIDER: S-EPMC10917503 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
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