Association between natriuretic peptides and C-reactive protein with frailty in heart failure: a systematic review and meta-analysis.

ABSTRACT:

Background

Heart failure (HF) and frailty are accompanied by a bidirectional relationship, sharing common risk factors including elevated levels of natriuretic peptides and inflammation. The aim of this study was to compare biomarkers associated with poor clinical outcomes, that is, plasma brain natriuretic peptide (BNP), N-terminal-pro B-type natriuretic peptide (NT-proBNP), and C-reactive protein (CRP) in patients with HF and frailty vs. patients with HF without frailty.

Methods

From inception until July 2023, PubMed, Scopus, Web of Science, and Cochrane Library a systematic literature search was conducted. To evaluate whether frailty is linked with greater levels of BNP, NT-proBNP, and CRP, a meta-analysis using a random-effects model was used to calculate the pooled effe

SUBMITTER: Prokopidis K 

PROVIDER: S-EPMC10917829 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature