Initial nutrient condition determines the recovery speed of quiescent cells in fission yeast.

ABSTRACT: Most of microbe cells spend the majority of their times in quiescence due to unfavorable environmental conditions. The study of this dominant state is crucial for understanding the basic cell physiology. Retained recovery ability is a critical property of quiescent cells, which consists of two features: how long the cells can survive (the survivability) and how fast they can recover (the recovery activity). While the survivability has been extensively studied under the background of chronological aging, how the recovery activity depends on the quiescent time and what factors influence its dynamics have not been addressed quantitatively. In this work, we systematically quantified both the survivability and the recovery activity of long-lived quiescent fission yeast cells at the single cell

SUBMITTER: Liu Q 

PROVIDER: S-EPMC10918017 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature