KAKU4 regulates leaf senescence through modulation of H3K27me3 deposition in the Arabidopsis genome.

ABSTRACT: Lamins are the major components of the nuclear lamina, which regulate chromatin structure and gene expression. KAKU4 is a unique nuclear lamina component in the nuclear periphery, modulates nuclear shape and size in Arabidopsis. The knowledge about the regulatory role of KAKU4 in leaf development remains limited. Here we found that knockdown of KAKU4 resulted in an accelerated leaf senescence phenotype, with elevated levels of H₂O₂ and hormones, particularly SA, JA, and ABA. Our results demonstrated the importance of KAKU4 as a potential negative regulator in age-triggered leaf senescence in Arabidopsis. Furthermore, we conducted combination analyses of transcriptomic and epigenomic data for the kaku4 mutant and WT leaves. The knockdown of KAKU4 lowered H3K27me3 depos

SUBMITTER: Cao Y 

PROVIDER: S-EPMC10919013 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature