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Genome Engineering as a Therapeutic Approach in Cancer Therapy: A Comprehensive Review.


ABSTRACT: Cancer is one of the foremost causes of mortality. The human genome remains stable over time. However, human activities and environmental factors have the power to influence the prevalence of certain types of mutations. This goes to the excessive progress of xenobiotics and industrial development that is expanding the territory for cancers to develop. The mechanisms involved in immune responses against cancer are widely studied. Genome editing has changed the genome-based immunotherapy process in the human body and has opened a new era for cancer treatment. In this review, recent cancer immunotherapies and the use of genome engineering technology are largely focused on.

SUBMITTER: Gemayel J 

PROVIDER: S-EPMC10919288 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature

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Genome Engineering as a Therapeutic Approach in Cancer Therapy: A Comprehensive Review.

Gemayel Jack J   Chebly Alain A   Kourie Hampig H   Hanna Colette C   Mheidly Kayane K   Mhanna Melissa M   Karam Farah F   Ghoussaini Daniel D   Najjar Paula El PE   Khalil Charbel C  

Advanced genetics (Hoboken, N.J.) 20240205 1


Cancer is one of the foremost causes of mortality. The human genome remains stable over time. However, human activities and environmental factors have the power to influence the prevalence of certain types of mutations. This goes to the excessive progress of xenobiotics and industrial development that is expanding the territory for cancers to develop. The mechanisms involved in immune responses against cancer are widely studied. Genome editing has changed the genome-based immunotherapy process i  ...[more]

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