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Vogt-Koyanagi-Harada-Like Disease with Loss of Visual Acuity due to Sunitinib Treatment Restored after Switch in Therapy: A Case Report.


ABSTRACT:

Introduction

In this paper, we report a case of visual impairment during treatment with sunitinib in a patient with metastatic renal cell carcinoma.

Methods

Retrospective chart review was used.

Case presentation

We describe a 74-year-old male with metastatic renal cell carcinoma who was treated with sunitinib and experienced severe loss of visual acuity due to serous retinal detachment and intraretinal fluid. Upon discontinuation of sunitinib, the retinal fluid resolved, and visual acuity was restored.

Conclusion

Serous retinal detachment has been described as a side effect of sunitinib use. Discontinuing sunitinib promptly resolved the subretinal fluid collections and restored vision.

SUBMITTER: van Olden MCS 

PROVIDER: S-EPMC10919912 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature

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Vogt-Koyanagi-Harada-Like Disease with Loss of Visual Acuity due to Sunitinib Treatment Restored after Switch in Therapy: A Case Report.

van Olden Mechteld C S MCS   de Jong-Hesse Yvonne Y   Vollebregt Tessa T   de Groot Stefanie S   Luelmo Saskia A C SAC   Marinkovic Marina M  

Case reports in ophthalmology 20240101 1


<h4>Introduction</h4>In this paper, we report a case of visual impairment during treatment with sunitinib in a patient with metastatic renal cell carcinoma.<h4>Methods</h4>Retrospective chart review was used.<h4>Case presentation</h4>We describe a 74-year-old male with metastatic renal cell carcinoma who was treated with sunitinib and experienced severe loss of visual acuity due to serous retinal detachment and intraretinal fluid. Upon discontinuation of sunitinib, the retinal fluid resolved, an  ...[more]

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