Molecular characterization of Escherichia coli producing extended-spectrum β-lactamase CTX-M-14 and CTX-M-28 in Mexico.

ABSTRACT: The spread of ESBL-producing Escherichia coli has constantly increased in both clinical and community infections. Actually, the main ESBL reported is the CTX-M family, which is widely disseminated between the Enterobacteriaceae family. The epidemiology of the CTX-M family shows the CTX-M-15 variant dominating worldwide, followed by CTX-M-14 and CTX-M-27. The specific ESBL-producing E. coli clones included mainly the sequence types ST131, ST405, and ST648. In this report, we present the molecular characterization of ESBL-producing E. coli clinical isolates from eight hospitals in Mexico. From a collection of 66 isolates, 39 (59%) were identified as bla_CTX-M-14 and bla_CTX-M-27 belonging to the group CTX-M-9. We identified 25 (38%) isolates, producing bla_CTX-M-28

SUBMITTER: Silva-Sanchez J 

PROVIDER: S-EPMC10920525 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature