Brain Frailty and Outcomes of Acute Minor Ischemic Stroke With Large-Vessel Occlusion.

ABSTRACT:

Background and purpose

The influence of imaging features of brain frailty on outcomes were investigated in acute ischemic stroke patients with minor symptoms and large-vessel occlusion (LVO).

Methods

This was a retrospective analysis of a prospective, multicenter, nationwide registry of consecutive patients with acute (within 24 h) minor (National Institutes of Health Stroke Scale score=0-5) ischemic stroke with anterior circulation LVO (acute minor LVO). Brain frailty was stratified according to the presence of an advanced white-matter hyperintensity (WMH) (Fazekas grade 2 or 3), silent/old brain infarct, or cerebral microbleeds. The primary outcome was a composite of stroke, myocardial infarction, and all-cause mortality within 1 year.

Results

In total, 1,067 patien

SUBMITTER: Park JW 

PROVIDER: S-EPMC10921043 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature