Exploration of the Healthy Donor Effect Among 0.6 Million Blood Donors in China: Longitudinal Study.

ABSTRACT:

Background

The World Health Organization emphasizes the importance of completely voluntary blood donation to maintain safe and sustainable blood supplies. However, the benefits of blood donation for donors, such as reducing the risk of disease, remain a topic of debate due to the existence of the healthy donor effect (HDE). This effect arises because of inherent health differences between blood donors and the general population, and it is also considered a methodological issue.

Objective

This study aims to generate a more detailed health profile of blood donors from a donor cohort study to mitigate and quantify the HDE and properly interpret the association between blood donation and disease outcomes among blood donors.

Methods

A retrospective cohort study was conduct

SUBMITTER: Su S 

PROVIDER: S-EPMC10921323 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature