A study on the radiomic correlation between CBCT and pCT scans based on modified 3D-RUnet image segmentation.

ABSTRACT:

Purpose

The present study is based on evidence indicating a potential correlation between cone-beam CT (CBCT) measurements of tumor size, shape, and the stage of locally advanced rectal cancer. To further investigate this relationship, the study quantitatively assesses the correlation between positioning CT (pCT) and CBCT in the radiomics features of these cancers, and examines their potential for substitution.

Methods

In this study, 103 patients diagnosed with locally advanced rectal cancer and undergoing neoadjuvant chemoradiotherapy were selected as participants. Their CBCT and pCT images were used to divide the participants into two groups: a training set and a validation set, with a 7:3 ratio. An improved conventional 3D-RUNet (CLA-UNet) deep learning model was trained

SUBMITTER: Yu Y 

PROVIDER: S-EPMC10921553 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature