Birth by caesarean section and semen quality in adulthood: a Danish population-based cohort study.

ABSTRACT:

Background

The caesarean section (CS) rate has increased worldwide and there is an increasing public and scientific interest in the potential long-term health consequences for the offspring. CS is related to persistent aberrant microbiota colonization in the offspring, which may negatively interfere with sex hormone homeostasis and thus potentially affect the reproductive health. It remains unknown whether adult sons' semen quality is affected by CS. We hypothesize that CS is associated with lower semen quality.

Methods

This study was based on the Fetal Programming of Semen Quality cohort (FEPOS, enrolled from 2017 to 2019) nested within the Danish National Birth Cohort (DNBC, enrolled from 1996 to 2002). A total of 5697 adult sons of mothers from the DNBC were invited to th

SUBMITTER: Huang K 

PROVIDER: S-EPMC10921573 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature