Geriatric assessment-derived deficit accumulation and patient-reported treatment burden in older adults with bladder cancer.

ABSTRACT:

Background

When a person's workload of healthcare exceeds their resources, they experience treatment burden. At the intersection of cancer and aging, little is known about treatment burden. We evaluated the association between a geriatric assessment-derived Deficit Accumulation Index (DAI) and patient-reported treatment burden in older adults with early-stage, non-muscle-invasive bladder cancer (NMIBC).

Methods

We conducted a cross-sectional survey of older adults with NMIBC (≥65 years). We calculated DAI using the Cancer and Aging Research Group's geriatric assessment and measured urinary symptoms using the Urogenital Distress Inventory-6 (UDI-6). The primary outcome was Treatment Burden Questionnaire (TBQ) score. A negative binomial regression with LASSO penalty was used t

SUBMITTER: Garg T 

PROVIDER: S-EPMC10922080 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature