Prediction of cognitive outcome after mild traumatic brain injury from acute measures of communication within brain networks.

ABSTRACT: A considerable but ill-defined proportion of patients with mild traumatic brain injury (mTBI) experience persistent cognitive sequelae; the ability to identify such individuals early can help their neurorehabilitation. Here we tested the hypothesis that acute measures of efficient communication within brain networks are associated with patients' risk for unfavorable cognitive outcome six months after mTBI. Diffusion and T₁-weighted magnetic resonance imaging, alongside cognitive measures, were obtained to map connectomes both one week and six months post injury in 113 adult patients with mTBI (71 males). For task-related brain networks, communication measures (characteristic path length, global efficiency, navigation efficiency) were moderately correlated with changes in cogniti

SUBMITTER: Imms P 

PROVIDER: S-EPMC10922490 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature