Clinical Phenotypes Supporting the Relationship Between Sleep Disturbance and Impairment of Placebo Effects.

ABSTRACT: Lack of good sleep or insomnia can lead to many health issues, including an elevated risk of cardiovascular disease, obesity, fatigue, low mood, and pain. While chronic pain negatively impacts sleep quality, the relationship between descending pain modulatory systems like placebo effects and sleep quality is not thoroughly known. We addressed this aspect in a cross-sectional study in participants with chronic pain. Placebo effects were elicited in a laboratory setting using thermal heat stimulations delivered with visual cues using classical conditioning and verbal suggestions. We estimated the levels of insomnia severity with the Insomnia Severity Index and the sleep quality with the Pittsburg Sleep Quality Index. The previous night's sleep continuity was assessed as total sleep time, sle

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10922511 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature