Association of Implantation Biopsy Findings in Living Donor Kidneys With Donor and Recipient Outcomes.

ABSTRACT:

Rationale & objective

Some living donor kidneys are found to have biopsy evidence of chronic scarring and/or glomerular disease at implantation, but it is unclear if these biopsy findings help predict donor kidney recovery or allograft outcomes. Our objective was to identify the prevalence of chronic histological changes and glomerular disease in donor kidneys, and their association with donor and recipient outcomes.

Study design

Retrospective cohort study.

Setting & participants

Single center, living donor kidney transplants from January 2010 to July 2022.

Exposure

Chronic histological changes, glomerular disease in donor kidney implantation biopsies.

Outcome

For donors, single-kidney estimated glomerular filtration rate (eGFR) increase, percent total e

SUBMITTER: Emmons BR 

PROVIDER: S-EPMC10922703 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature