Prenatal air pollution exposure in relation to the telomere-mitochondrial axis of aging at birth: A systematic review.

ABSTRACT:

Background

Telomere length (TL) and mitochondrial DNA (mtDNA) are central markers of vital biological mechanisms, including cellular aging. Prenatal air pollution exposure may impact molecular markers of aging leading to adverse health effects.

Objective

To perform a systematic review on human population-based studies investigating the association between prenatal air pollution exposure and TL or mtDNA content at birth.

Methodology

Searches were undertaken on PubMed and Web of Science until July 2023. The framework of the review was based on the PRISMA-P guidelines.

Results

Nineteen studies studied prenatal air pollution and TL or mtDNA content at birth. Studies investigating TL or mtDNA content measured at any other time or did not evaluate prenatal air pollut

SUBMITTER: Mishra S 

PROVIDER: S-EPMC10922941 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature