Battle of the biopsies: Role of tissue and liquid biopsy in hepatocellular carcinoma.

ABSTRACT: The diagnosis and management of hepatocellular carcinoma (HCC) have improved significantly in recent years. With the introduction of immunotherapy-based combination therapy, there has been a notable expansion in treatment options for patients with unresectable HCC. Simultaneously, innovative molecular tests for early detection and management of HCC are emerging. This progress prompts a key question: as liquid biopsy techniques rise in prominence, will they replace traditional tissue biopsies, or will both techniques remain relevant? Given the ongoing challenges of early HCC detection, including issues with ultrasound sensitivity, accessibility, and patient adherence to surveillance, the evolution of diagnostic techniques is more relevant than ever. Furthermore, the accurate stratification

SUBMITTER: Lehrich BM 

PROVIDER: S-EPMC10923008 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature