Clinical outcomes of stereotactic body radiation therapy for malignant pleural mesothelioma.

ABSTRACT:

Background

The objective of this study is to determine the outcomes and toxicities of patients with malignant pleural mesothelioma (MPM) treated with stereotactic body radiotherapy (SBRT).

Materials and methods

Data were extracted from an institutional tumor registry for patients diagnosed with mesothelioma and treated with SBRT. Kaplan-Meier and Cox regression analyses were employed to determine local control (LC) and overall survival (OS).

Results

Forty-four patients with 59 total treated tumors from December 2006 to April 2022 were identified. Fifty-one (86.4 %) cases had oligoprogressive disease (five sites or less). The median prescription dose delivered was 3000 cGy in 5 fractions (range: 2700-6000 cGy in 3-8 fractions). Fifty-one (86.4 %) tumors were in the ple

SUBMITTER: Shin JY 

PROVIDER: S-EPMC10923065 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature