Do Infectious Diseases After Kidney Retransplantation Differ From Those After First Kidney Transplantation?

ABSTRACT:

Background

Infectious diseases (IDs) are highly relevant after solid organ transplantation in terms of morbidity and mortality, being among the most common causes of death. Patients undergoing kidney retransplantation (re-K-Tx) have been already receiving immunosuppressive therapy over a prolonged period, potentially facilitating subsequent infections. Comparing ID events after re-K-Tx and first kidney transplantation (f-K-Tx) can delineate patterns and risks of ID events associated with prolonged immunosuppression.

Methods

We included adult patients with records on f-K-Tx and re-K-Tx in the Swiss Transplant Cohort Study. We analyzed ID events after f-K-Tx and re-K-Tx within the same patients and compared infection rates, causative pathogens, and infection sites. Recurrent t

SUBMITTER: Kusejko K 

PROVIDER: S-EPMC10923290 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature