Impact of Early Rejection Treatment on Infection Development in Kidney Transplant Recipients: A Propensity Analysis.

ABSTRACT:

Introduction

The impact of renal allograft rejection treatment on infection development has not been formally defined in the literature.

Methods

We conducted a retrospective cohort study of 185 rejection (case) and 185 nonrejection (control) kidney transplant patients treated at our institution from 2014 to 2020 to understand the impact of rejection on infection development. Propensity scoring was used to match cohorts. We collected data for infections within 6 months of rejection for the cases and 18 months posttransplant for controls.

Results

In 370 patients, we identified 466 infections, 297 in the controls, and 169 in the cases. Urinary tract infections (38.9%) and cytomegalovirus viremia (13.7%) were most common. Cumulative incidence of infection between the case

SUBMITTER: Gupta S 

PROVIDER: S-EPMC10923621 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature