Validation of an ICD-code-based case definition for psychotic illness across three health systems.

ABSTRACT:

Background and hypothesis

Early detection of psychosis is critical for improving outcomes. Algorithms to predict or detect psychosis using electronic health record (EHR) data depend on the validity of the case definitions used, typically based on diagnostic codes. Data on the validity of psychosis-related diagnostic codes is limited. We evaluated the positive predictive value (PPV) of International Classification of Diseases (ICD) codes for psychosis.

Study design

Using EHRs at three health systems, ICD codes comprising primary psychotic disorders and mood disorders with psychosis were grouped into five higher-order groups. 1,133 records were sampled for chart review using the full EHR. PPVs (the probability of chart-confirmed psychosis given ICD psychosis codes) were calcul

SUBMITTER: Deo AJ 

PROVIDER: S-EPMC10925367 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature