Using Trajectories of Bedside Vital Signs to Identify COVID-19 Subphenotypes.

ABSTRACT:

Background

Trajectories of bedside vital signs have been used to identify sepsis subphenotypes with distinct outcomes and treatment responses. The objective of this study was to validate the vitals trajectory model in a multicenter cohort of patients hospitalized with COVID-19 and to evaluate the clinical characteristics and outcomes of the resulting subphenotypes.

Research question

Can the trajectory of routine bedside vital signs identify COVID-19 subphenotypes with distinct clinical characteristics and outcomes?

Study design and methods

The study included adult patients admitted with COVID-19 to four academic hospitals in the Emory Healthcare system between March 1, 2020, and May 31, 2022. Using a validated group-based trajectory model, we classified patients into

SUBMITTER: Bhavani SV 

PROVIDER: S-EPMC10925543 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature