Associations of Plasma Omega-3 Fatty Acids With Progression and Survival in Pulmonary Fibrosis.

ABSTRACT:

Background

Preclinical experiments suggest protective effects of omega-3 fatty acids and their metabolites in lung injury and fibrosis. Whether higher intake of omega-3 fatty acids is associated with disease progression and survival in humans with pulmonary fibrosis is unknown.

Research question

What are the associations of plasma omega-3 fatty acid levels (a validated marker of omega-3 nutritional intake) with disease progression and transplant-free survival in pulmonary fibrosis?

Study design and methods

Omega-3 fatty acid levels were measured from plasma samples of patients with clinically diagnosed pulmonary fibrosis from the Pulmonary Fibrosis Foundation Patient Registry (n = 150), University of Virginia (n = 58), and University of Chicago (n = 101) cohorts. The

SUBMITTER: Kim JS 

PROVIDER: S-EPMC10925547 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature