Elevated plasma myoglobin level is closely associated with type 2 diabetic kidney disease.

ABSTRACT:

Background

Diabetic kidney disease (DKD) is the most frequent complication in patients with type 2 diabetes mellitus (T2DM). It causes a chronic and progressive decline in kidney function, and ultimately patients require renal replacement therapy. To date, an increasing number of clinical studies have been conducted to explore the potential and novel biomarkers, which can advance the diagnosis, estimate the prognosis, and optimize the therapeutic strategies at the early stage of DKD. In the current study, we sought to investigate the association of plasma myoglobin with DKD.

Methods

A total of 355 T2DM patients with DKD and 710 T2DM patients without DKD were enrolled in this study. Laboratory parameters including blood cell count, hemoglobin A1c, biochemical parameters, and

SUBMITTER: Yang L 

PROVIDER: S-EPMC10925879 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature