Associations between actigraphy-measured sleep duration, continuity, and timing with mortality in the UK Biobank.

ABSTRACT:

Study objectives

To examine the associations between sleep duration, continuity, timing, and mortality using actigraphy among adults.

Methods

Data were from a cohort of 88 282 adults (40-69 years) in UK Biobank that wore a wrist-worn triaxial accelerometer for 7 days. Actigraphy data were processed to generate estimates of sleep duration and other sleep characteristics including wake after sleep onset (WASO), number of 5-minute awakenings, and midpoint for sleep onset/wake-up and the least active 5 hours (L5). Data were linked to mortality outcomes with follow-up to October 31, 2021. We implemented Cox models (hazard ratio, confidence intervals [HR, 95% CI]) to quantify sleep associations with mortality. Models were adjusted for demographics, lifestyle factors, and medical c

SUBMITTER: Saint-Maurice PF 

PROVIDER: S-EPMC10925955 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature