Evaluating the progression to abnormal thyrotropin in euthyroid preconception women: a population-based study.

ABSTRACT:

Background

Abnormal preconception thyrotropin levels were associated with fecundability and adverse fetomaternal outcomes, however, little is known regarding the natural change of serum thyrotropin in euthyroid preconception women. Thus, we performed a population-based study to evaluate the progression to abnormal thyrotropin in euthyroid preconception women.

Methods

This retrospective cohort study used data from the National Free Prepregnancy Checkups Project (NFPCP) collected between 2010 and 2020. Female Han Chinese participants aged 20-49 years who had two repeated NFPCP participations with a time interval of 1.5-3.0 years, confirmed non-pregnant status within this duration, and normal thyrotropin levels during their first participation were included for the analysis of

SUBMITTER: Gao R 

PROVIDER: S-EPMC10926655 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature