Association of Periprocedural Inflammatory Activation With Increased Risk for Early Coronary Stent Thrombosis.

ABSTRACT:

Background

Stent thrombosis is a rare but deleterious event. Routine coronary angiography with percutaneous coronary intervention (PCI) is often deferred in the presence of laboratory markers of acute inflammation to prevent complications. The aim of this study was to investigate whether an acute inflammatory state is associated with an increased risk of early stent thrombosis.

Methods and results

Within a prospective single-center registry, the association between preprocedural acute inflammatory activation, defined as C-reactive protein plasma levels >50 mg/L or a leukocyte count >12 g/L, and occurrence of early (≤30 days) stent thrombosis was evaluated. In total, 11 327 patients underwent PCI and of those, 6880 patients had laboratory results available. 49.6% of the study

SUBMITTER: Krychtiuk KA 

PROVIDER: S-EPMC10926812 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature