Incidence and survival of second primary non-Hodgkin lymphoma: A Surveillance, Epidemiology, and End Results-based cohort study.

ABSTRACT:

Background

The aim of this study was to investigate patient survival and factors associated with survival in second primary non-Hodgkin lymphoma (NHL) compared with the first primary NHL.

Methods

The retrospective cohort study used data from the Surveillance, Epidemiology, and End Results (SEER) database between 2000 and 2014. Demographic characteristics, histological types, Ann Arbor stage, and treatment information were collected. Cox proportional hazard models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for factors associated with overall survival (OS) and cancer-specific survival (CSS) in the first and second primary NHLs.

Results

Of 318,168 cases followed for 5 years, 299,248 patients developed the first primary NHL and 18,920 pat

SUBMITTER: Yu N 

PROVIDER: S-EPMC10927152 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature