Evaluation of Triple Whammy Prescriptions After the Implementation of a Drug Safety Algorithm.

ABSTRACT:

Background and objective

The term triple whammy (TW) refers to the concomitant use of non-steroidal anti-inflammatory drugs, diuretics, and angiotensin system inhibitors; this combination significantly increases the risk of acute kidney injury (AKI). To prevent this serious complication, we developed an electronic algorithm that detects TW prescriptions in patients with additional risk factors such as old age and impaired kidney function. The algorithm alerts a clinical pharmacist who then evaluates and forwards the alert to the prescribing physician.

Methods

We evaluated the performance of this algorithm in a retrospective observational study of clinical data from all adult patients admitted to the Cantonal Hospital of Aarau in Switzerland in 2021. We identified all patient

SUBMITTER: Dahmke H 

PROVIDER: S-EPMC10928054 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature