Metastatic gallbladder cancer presenting as numb chin syndrome: A case report and literature review.

ABSTRACT: Gallbladder cancer (GBC) is an uncommon malignancy that is highly aggressive in the advanced stages. However, it rarely metastasizes to the mandible. Numb chin syndrome (NCS) is a rare neurological manifestation associated with various underlying causes, including occult primary cancers and distant metastases. It is often considered to be a significant indicator of malignancy, and thorough investigation is essential in the presence of unclear etiology. The current study reported on the case of a 69-year-old Japanese woman who presented with numbness and mild pain in the lower lip and chin area for three months. No other systemic symptoms were observed. Immunocytochemical examination revealed the presence of an adenocarcinoma and TNM staging as per the Union for International Cancer Control

SUBMITTER: Murahashi M 

PROVIDER: S-EPMC10928479 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature