Beating Heart Transplant Procedures Using Organs From Donors With Circulatory Death.

ABSTRACT:

Importance

The use of ex vivo normothermic organ perfusion has enabled the use of deceased after circulatory death (DCD) donors for heart transplants. However, compared with conventional brain death donation, DCD heart transplantation performed with ex vivo organ perfusion involves an additional period of warm and cold ischemia, exposing the allograft to multiple bouts of ischemia reperfusion injury and may contribute to the high rates of extracorporeal membrane oxygenation usage after DCD heart transplantation.

Objective

To assess whether the beating heart method of DCD heart transplantation is safe and whether it has an acceptable rate of extracorporeal membrane oxygenation use postoperatively.

Design, setting, and participants

This case series includes 10 patients

SUBMITTER: Krishnan A 

PROVIDER: S-EPMC10928498 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature