Influence of size, volume concentration and aggregation state on magnetic nanoparticle hyperthermia properties versus excitation conditions.

ABSTRACT: Treatment planning in magnetic hyperthermia requires a thorough knowledge of specific loss power of magnetic nanoparticles as a function of size and excitation conditions. Moreover, in biological tissues the magnetic nanoparticles can aggregate into clusters, making the evaluation of their heating performance more challenging because of the magnetostatic dipole-dipole interactions. In this paper, we present a comprehensive modelling analysis of 10-40 nm sized spherical magnetite (Fe₃O₄) nanoparticles, investigating how their heating properties are influenced by magnetic field parameters (peak amplitude and frequency), and by volume concentration and aggregation state. The analysis is performed by means of an in-house micromagnetic numerical model, which solves the Lan

SUBMITTER: Ferrero R 

PROVIDER: S-EPMC10929599 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature