Acute kidney injury in patients treated with immune checkpoint inhibitors: a single-center retrospective study.

ABSTRACT:

Background

Immune checkpoint inhibitor-associated acute kidney injury (ICI-AKI) is the most common renal complication and has attracted increasing amounts of attention. However, studies on this topic in Chinese cancer patients are very limited. Therefore, we conducted a retrospective study on the incidence, risk factors, clinical features and renal recovery of ICI-AKI in all patients with malignancies treated with ICIs in Shandong Provincial Hospital Affiliated to Shandong First Medical University.

Methods

In this single-center retrospective cohort study, the data of 904 patients who received immune checkpoint inhibitors (ICIs) treatment were retrospectively analyzed. Multivariable logistic regression was used to identify the predictors of ICI-AKI.

Results

A total of

SUBMITTER: Zhou P 

PROVIDER: S-EPMC10930152 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature