A mathematical model to assess the effectiveness of test-trace-isolate-and-quarantine under limited capacities.

ABSTRACT: Diagnostic testing followed by isolation of identified cases with subsequent tracing and quarantine of close contacts-often referred to as test-trace-isolate-and-quarantine (TTIQ) strategy-is one of the cornerstone measures of infectious disease control. The COVID-19 pandemic has highlighted that an appropriate response to outbreaks of infectious diseases requires a firm understanding of the effectiveness of such containment strategies. To this end, mathematical models provide a promising tool. In this work, we present a delay differential equation model of TTIQ interventions for infectious disease control. Our model incorporates the assumption of limited TTIQ capacities, providing insights into the reduced effectiveness of testing and tracing in high prevalence scenarios. In addition, we

SUBMITTER: Heidecke J 

PROVIDER: S-EPMC10931449 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature