Use of microRNAs as Diagnostic, Prognostic, and Therapeutic Tools for Glioblastoma.

ABSTRACT: Glioblastoma (GB) is the most aggressive and common type of cancer within the central nervous system (CNS). Despite the vast knowledge of its physiopathology and histology, its etiology at the molecular level has not been completely understood. Thus, attaining a cure has not been possible yet and it remains one of the deadliest types of cancer. Usually, GB is diagnosed when some symptoms have already been presented by the patient. This diagnosis is commonly based on a physical exam and imaging studies, such as computed tomography (CT) and magnetic resonance imaging (MRI), together with or followed by a surgical biopsy. As these diagnostic procedures are very invasive and often result only in the confirmation of GB presence, it is necessary to develop less invasive diagnostic and prognostic

SUBMITTER: Valle-Garcia D 

PROVIDER: S-EPMC10931459 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature