Identification and Structural Characterization of Degradation Products of Linagliptin by Mass Spectrometry Techniques.

ABSTRACT: As part of the development and production of pharmaceuticals, the purity of Active Pharmaceutical Ingredients stands as a fundamental parameter that significantly influences the quality, safety, and efficacy of the final drug product. Impurities in Active Pharmaceutical Ingredients are various unwanted substances that can appear during the whole manufacturing process, from raw materials to the final product. These impurities can stem from multiple sources, including starting materials, intermediates, reagents, solvents, and even degradation products resulting from exposure to environmental factors such as heat, light, or moisture. Their presence can potentially compromise the therapeutic effect of the drug, introduce unexpected side effects, or even pose safety risks to patients. This stud

SUBMITTER: Liana A 

PROVIDER: S-EPMC10932084 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature