Genetic Characterization of Dilated Cardiomyopathy in Romanian Adult Patients.

ABSTRACT: Dilated cardiomyopathy (DCM) represents a group of disorders affecting the structure and function of the heart muscle, leading to a high risk of heart failure and sudden cardiac death (SCD). DCM frequently involves an underlying genetic etiology. Genetic testing is valuable for risk stratification, treatment decisions, and family screening. Romanian population data on the genetic etiology of DCM are lacking. We aimed to investigate the genetic causes for DCM among Romanian adult patients at tertiary referral centers across the country. Clinical and genetic investigations were performed on adult patients presenting to tertiary hospitals in Romania. The genetic investigations used next-generation sequencing panels of disease-associated DCM genes. A total of 122 patients with DCM underwent ge

SUBMITTER: Voinescu OR 

PROVIDER: S-EPMC10932273 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature