Isolated teratozoospermia: revisiting its relevance in male infertility: a narrative review.

ABSTRACT:

Background and objective

Basic semen analysis is the first step in the evaluation of male infertility. It includes an assessment of sperm morphology which is believed to reflect on overall spermatogenesis and sperm function. Teratozoospermia, defined as abnormal sperm morphology, is frequently present in association with severe oligoasthenozoospermia, but isolated teratozoospermia (in the presence of normal counts and motility) is a poorly understood clinical entity with conflicting implications in terms of fertility potential and treatment strategies. The following paper aims to: (I) discuss the classification of sperm morphology, causes, and molecular mechanism of teratozoospermia; (II) analyze the clinical significance and potential treatment options of isolated teratozoospermia

SUBMITTER: Atmoko W 

PROVIDER: S-EPMC10932644 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature