An unexpected case of large cell neuroendocrine carcinoma of the colon: a case report.

ABSTRACT:

Background

Patients presenting with large cell neuroendocrine carcinomas (LCNECs) comprise a small minority of total colon and rectal cancers (1-2%) with poor prognostic outcomes in lieu of late diagnosis and metastasis at the point of diagnosis.

Case description

We report a case presentation of a 69-year-old male presenting with diffuse, non-severe upper abdominal pain and a positive at-home colon cancer screening test. At the time of presentation, the patient was negative for constipation or blood in stool. The patient underwent a colonoscopy with biopsy results positive for LCNEC within the proximal ascending colon. A right hemicolectomy was performed with subsequent pathology indicating a poorly differentiated LCNEC with 4/18 positive nodes and final pathology showing st

SUBMITTER: Nnawuba K 

PROVIDER: S-EPMC10932652 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature