BMP6 inhibits gastric cancer growth and predicts good prognosis.

ABSTRACT:

Background

Gastric cancer (GC) is a common tumors in the digestive tract, and effective treatment methods are still lacking. Bone morphogenetic protein 6 (BMP6) is closely related to the occurrence and development of various tumors, but its relevance to GC is still unclear. The aim of the study was to explore the relationship between BMP6 and the occurrence and development of GC.

Methods

In this study, we investigated the relationship between BMP6 and the prognosis of GC patients using bioinformatics technology and clinical tissue samples. We also explored the connection between BMP6 and the biological behavior of GC cells through molecular biology experiments and relevant in vivo animal experiments. Finally, we examined the mechanisms by which BMP6 inhibits the onset

SUBMITTER: Song C 

PROVIDER: S-EPMC10932659 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature